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Therapeutic Index

Asthom
Asthom  Tablets
Asthom Forte  Tablets
Asthom Forte ST Tablets
Asthom  Syrup

Composition
Asthom  Tablets
Each tablet contains Salbutamol Sulphate IP equivalent to Salbutamol IP
2 mg and Theophylline anhydrous IP 100 mg
Asthom Forte  Tablets
Each tablet contains Salbutamol Sulphate IP equivalent to Salbutamol IP 4
mg and Theophylline anhydrous IP 200 mg
Asthom Forte ST Tablets
Each sustained-release uncoated tablet contains ... Salbutamol Sulphate
IP equivalent to Salbutamol IP 4 mg and Theophylline anhydrous IP 300
mg
Asthom  Syrup
Each 5 ml contains Salbutamol Sulphate IP equivalent to Salbutamol IP
1 mg and Theophylline anhydrous IP 50 mg in a flavoured syrup base q.s.

Indications
Asthom  and Asthom Forte  are particularly indicated for patients who experience side effects with maximal therapeutic doses of either theophylline or salbutamol alone and patients with severe asthma
who require more than one drug from any class of bronchodilators. Asthom Forte ST is indicated for long-term maintenance bronchodilator therapy in patients with obstructive airway disease, i.e. asthma and COPD,
including patients with nocturnal asthma.

Dosage and Administration
Optimum dosage must be individualised due to variability of theophylline pharmacokinetics with age, diet, smoking, cardiac failure and liver disease. The usual starting dose is one tablet of Asthom  or 10 ml (one measure) of Asthom  Syrup, thrice daily. In select patients, if further bronchodilation is required, dosage may be increased to one tablet of
Asthom Forte  thrice daily. Asthom Forte ST should be taken at 12-hourly intervals. In those asthmatics whose condition deteriorates despite the above therapy, further increase in the recommended dosage is not advisable.
Alternative or additional therapy including corticosteroids and oxygen should be instituted promptly in severe cases.

Contraindications
Hypersensitivity to xanthine derivatives.

Presentation
Asthom                              Blister pack of 10 tablets
Asthom Forte                    Blister pack of 10 tablets
Asthom Forte ST               Blister pack of 10 tablets
Asthom  Syrup                  Bottle of 100 ml
           
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